Peerless Bosses
There are 8 boss creatures.
Mondain's Legacy
Stygian Abyss
To face a boss you first have to do the matching quest. There is a different quest for each boss creature.
These quests require you to collect the boss's "keys". Once you have those key items, place them at specific spots to make the boss appear.
Bosses appear in their own dedicated areas, and you end up with 3 "master keys" which, when double clicked, take you and the people in your party into the boss area. You can hand these master keys to other players or hold on to them, so you can leave the boss area and come back.
Once you enter the boss area you have roughly 1 hour to kill the boss. While a boss is active, other parties cannot activate the same boss -- they have to wait for you to finish. If you don't finish in time you can be thrown out of the area. Also, if every player leaves the boss area, the boss creature despawns.
The boss creatures carry serious loot. Every one of them drops high-value magical ingredients used to craft artifacts. On top of that, each has rare items only it can give. There are decorative items as well as usable ones.
Bedlam - Monstrous Interred Grizzle
Monstrous Interred Grizzle -- to face this boss you need to enter Bedlam. To do that you must first be on the quest that grants access to the area. In Umbra, next to Bloodletter, talk to "Aernya the Mistress of Admissions" and take the "Mistaken Identity" quest.
Complete the steps that grant access to Bedlam, but do not finish the quest entirely. Once you have access, double click the Iron Maiden at Bloodletter's place to enter Bedlam.
In the library inside Bedlam, talk to "Master Cohenn the Librarian" and take the "Misplaced" quest and complete it. To earn the reward for this quest you need to collect 5 "Disintegrating Thesis Notes". This item drops with a chance from the creatures in Bedlam named Lady Jennifyr, Lady Marai, Master Jonath, Master Theophilus, Master Mikael, Sir Patrick.
When you complete the quest your reward is the
Librarian's Key. Drop the Librarian's Key on the table inside the lair house in Bedlam and you get the master key you need for Monstrous Interred Grizzle.
Note: The Librarian's Key disappears from the world 1 hour after you obtain it.
Blighted Grove - Lady Melisande
Lady Melisande -- to face this boss you need to enter Blighted Grove. To do that you first need a
bone machete. To make a bone machete, talk to "Jamal the Fisherman" just outside the Blighted Grove entrance and complete the "Vile Poison" quest to learn the recipe needed to craft the weapon, then make a bone machete (or a few, since they break over time). That opens the path into Blighted Grove.
Note: You craft the "Bone Machete" from the Blacksmith menu. Also, to learn the recipe by completing the "Vile Poison quest, your Blacksmith skill must be 45 or higher.
Once you are inside Blighted Grove, find the quest giver "The Frightened Dryad" and complete the "Bound to the Land" quest to receive her blessing
(Dryad's Blessing). To get the master key you need for the Lady Melisande area, place the blessing you received (Dryad's Blessing) in the basket next to the Frightened Dryad.
Note: The Dryad's Blessing you earn from the quest disappears after 6 hours.
Citadel - Travesty
To reach the entrance to the Citadel, take a moongate and pick "Isamu-Jima" from the "Tokuno Islands" map. From the Tokuno map, double click the chest on the ground to enter the Citadel. Before you can get in, you must be in the middle of the Evidence or Black Order Badges quest given by "Sarakki the Notary" in the city of Britain.
To get to Travesty's area you need to obtain the
Serpent's Fang Key, Tiger's Claw Key and Dragon's Flame Key. These keys come from 3 members of the Black Order: The Serpent's Fang High Executioner, The Tiger's Claw Master and The Dragon's Flame Grand Mage.
Once you have all 3 keys, place them on the table in the Citadel's entrance room to enter the Travesty area.
Note: The keys you get from the creatures disappear after 6 hours.
Palace of Paroxysmus - Chief Paroxysmus
The Palace of Paroxysmus lies north of Papua, in the middle of the Lost Lands. To get in you need either a magical rope bought for 5000 gold or an acid proof rope made by a carpenter.
To fight Paroxysmus you must collect 4 items and place them in the cauldron outside the area. Coagulated Legs, Gelatanous Skull and Partially Digested drop at random from the corpses of corrosive slimes. The Spleen of the Putrefier drops at random from the Putrefier's corpse. Once you put these 4 items in the cauldron you receive the key to the area.
Prism of Light - Shimmering Effusion
Buy a ticket from Lefty the Ticket Seller outside the entrance in Nujel'm (for 10,000 gold) and enter the Prism of Light.
The Shimmering Effusion has 6 separate altars. Each altar needs a different type of crystal placed on it, and once all 6 altars are filled you get the master key. The altars appear as 6 stone pillars in a room with guardians.
The crystal types: broken crystals, crushed crystals, jagged crystals, pieces of crystal, scattered crystals and shattered crystals. Each crystal type is found at random in the corpse of a specific monster. Those monsters are: crystal daemon, crystal sea serpent, crystal hydra, crystal lattice seeker, crystal vortice and unfrozen mummies.
Twisted Weald - Dread Horn
To get into Twisted Weald you must be on the Dreadhorn quest given by the quest giver in the Elf city Heartwood-- reached from the center of Yew (location) -- named "Lorekeeper Calendor" (click for the location). The entrance to Twisted Weald is the faerie circle inside the "Mushroom Cave" (click for the location) in Ilshenar.
To get onto Dread Horn's island you must collect 6 items and drop them on the Statue of the Faie. That statue stands inside the stone circle on the east side of the island.
2 of those items, 
Blighted Cotton and 
Thorny Briar, can be picked up off the ground inside Twisted Weald. The other 4 items are found in the corpses of Named creatures:
Stygian Abyss Dungeon - Medusa
To enter Medusa's lair you need 4 serpent eggs (
Rare Serpent Eggs ). You can get the eggs from the serpent nests (Serpent Nest) in the "Serpent Lair" area of the Stygian Abyss Dungeon. Using a "Snake Charmer Flute" makes collecting these eggs much easier.
Once you have the eggs, place them on the altar in "Medusa's Lair" and you can enter the area where Medusa is.
Note: The eggs taken from the serpent nests (Serpent Nest) disappear after 12 hours.
Stygian Abyss Dungeon - Stygian Dragon
To enter the Stygian Dragon's lair you need 4
Draconic Orbs. This item drops from the creatures Fairy Dragon, Forgotten Servant.
Once you have 4 Draconic Orbs, place them on the altar in the "Stygian Dragon's lair" and you can enter the area where the Stygian Dragon is.
Note: The Draconic Orbs you get from the creatures disappear after 12 hours.
Mondain's Legacy
- Dread Horn - Twisted Weald
- Travesty - Citadel
- Chief Paroxysmus - Palace of Paroxysmus
- Lady Melisande - Blighted Grove
- Monstrous Interred Grizzle - Bedlam
- Shimmering Effusion - Prism of Light
Stygian Abyss
To face a boss you first have to do the matching quest. There is a different quest for each boss creature.
These quests require you to collect the boss's "keys". Once you have those key items, place them at specific spots to make the boss appear.
Bosses appear in their own dedicated areas, and you end up with 3 "master keys" which, when double clicked, take you and the people in your party into the boss area. You can hand these master keys to other players or hold on to them, so you can leave the boss area and come back.
Once you enter the boss area you have roughly 1 hour to kill the boss. While a boss is active, other parties cannot activate the same boss -- they have to wait for you to finish. If you don't finish in time you can be thrown out of the area. Also, if every player leaves the boss area, the boss creature despawns.
The boss creatures carry serious loot. Every one of them drops high-value magical ingredients used to craft artifacts. On top of that, each has rare items only it can give. There are decorative items as well as usable ones.
Bedlam - Monstrous Interred Grizzle
Monstrous Interred Grizzle -- to face this boss you need to enter Bedlam. To do that you must first be on the quest that grants access to the area. In Umbra, next to Bloodletter, talk to "Aernya the Mistress of Admissions" and take the "Mistaken Identity" quest.
Complete the steps that grant access to Bedlam, but do not finish the quest entirely. Once you have access, double click the Iron Maiden at Bloodletter's place to enter Bedlam.
In the library inside Bedlam, talk to "Master Cohenn the Librarian" and take the "Misplaced" quest and complete it. To earn the reward for this quest you need to collect 5 "Disintegrating Thesis Notes". This item drops with a chance from the creatures in Bedlam named Lady Jennifyr, Lady Marai, Master Jonath, Master Theophilus, Master Mikael, Sir Patrick.
When you complete the quest your reward is the
Note: The Librarian's Key disappears from the world 1 hour after you obtain it.
Blighted Grove - Lady Melisande
Lady Melisande -- to face this boss you need to enter Blighted Grove. To do that you first need a
Note: You craft the "Bone Machete" from the Blacksmith menu. Also, to learn the recipe by completing the "Vile Poison quest, your Blacksmith skill must be 45 or higher.
Once you are inside Blighted Grove, find the quest giver "The Frightened Dryad" and complete the "Bound to the Land" quest to receive her blessing
(Dryad's Blessing). To get the master key you need for the Lady Melisande area, place the blessing you received (Dryad's Blessing) in the basket next to the Frightened Dryad.
Citadel - Travesty
To reach the entrance to the Citadel, take a moongate and pick "Isamu-Jima" from the "Tokuno Islands" map. From the Tokuno map, double click the chest on the ground to enter the Citadel. Before you can get in, you must be in the middle of the Evidence or Black Order Badges quest given by "Sarakki the Notary" in the city of Britain.
To get to Travesty's area you need to obtain the
Once you have all 3 keys, place them on the table in the Citadel's entrance room to enter the Travesty area.
Palace of Paroxysmus - Chief Paroxysmus
The Palace of Paroxysmus lies north of Papua, in the middle of the Lost Lands. To get in you need either a magical rope bought for 5000 gold or an acid proof rope made by a carpenter.
To fight Paroxysmus you must collect 4 items and place them in the cauldron outside the area. Coagulated Legs, Gelatanous Skull and Partially Digested drop at random from the corpses of corrosive slimes. The Spleen of the Putrefier drops at random from the Putrefier's corpse. Once you put these 4 items in the cauldron you receive the key to the area.
Prism of Light - Shimmering Effusion
Buy a ticket from Lefty the Ticket Seller outside the entrance in Nujel'm (for 10,000 gold) and enter the Prism of Light.
The Shimmering Effusion has 6 separate altars. Each altar needs a different type of crystal placed on it, and once all 6 altars are filled you get the master key. The altars appear as 6 stone pillars in a room with guardians.
The crystal types: broken crystals, crushed crystals, jagged crystals, pieces of crystal, scattered crystals and shattered crystals. Each crystal type is found at random in the corpse of a specific monster. Those monsters are: crystal daemon, crystal sea serpent, crystal hydra, crystal lattice seeker, crystal vortice and unfrozen mummies.
Twisted Weald - Dread Horn
To get into Twisted Weald you must be on the Dreadhorn quest given by the quest giver in the Elf city Heartwood-- reached from the center of Yew (location) -- named "Lorekeeper Calendor" (click for the location). The entrance to Twisted Weald is the faerie circle inside the "Mushroom Cave" (click for the location) in Ilshenar.
To get onto Dread Horn's island you must collect 6 items and drop them on the Statue of the Faie. That statue stands inside the stone circle on the east side of the island.
Blighted Cotton and Thorny Briar, can be picked up off the ground inside Twisted Weald. The other 4 items are found in the corpses of Named creatures:- "Gnaw" ->
Gnaw's Fang, - "Irk" ->
Irk's Brain, - "Lady Sabrix" ->
Sabrix's Eye - "Giant Black Widow" ->
Lissith's Silk.
Stygian Abyss Dungeon - Medusa
To enter Medusa's lair you need 4 serpent eggs (
Once you have the eggs, place them on the altar in "Medusa's Lair" and you can enter the area where Medusa is.
Stygian Abyss Dungeon - Stygian Dragon
To enter the Stygian Dragon's lair you need 4
Once you have 4 Draconic Orbs, place them on the altar in the "Stygian Dragon's lair" and you can enter the area where the Stygian Dragon is.
Source: Quingis UO